Engineered to make therapeutic molecules perform

Bio-Courier® Platform

SiSaf’s first to market Bio-Courier platform technology leverages the unique properties of biologically friendly silicon, lipids and amino acids to address the significant challenges of stability, solubility, targeting and controlled release of complex therapeutic molecules.

Its customizable design and fabrication provide unparalleled flexibility with respect to therapeutic molecule type and target cell location. Bio-Couriers are biocompatible and fully biodegradable, eliminating the accumulation of potentially toxic or immune-activating material. ProSilic®, our lead Bio-Courier is 100% bioabsorbable as it fully dissipates to Ortho-Silicic Acid (OSA), the bioavailable form of silicon and essential micromineral for cellular health.

Cost-effective, scaled manufacturing provides unparalleled flexibility to address both rare diseases and large patient populations.

Increased drug stability and solubility.

Localisation and Targeting

Controlled release

EXAMPLES OF MOLECULES FORMULATED WITH BIO-COURIERS

Vitamins

Peptides/Proteins

Enzymes

Nucleic Acid

Antibodies

Lipids

Bio-Couriers are
extremely versatile

  • Very high surface area (>700 m2/g)
  • Pore volume of > 1 cm3/g
  • Stable nanostructure
  • Tunable pore diameter (2-10 nm)
  • Two functional surfaces (interior and exterior)
  • Control of particle size and shapes
  • Modifiable particle surface

Safety is built in

Bio-Couriers are biologically friendly, the components are U.S. FDA Generally Recognized As Safe (GRAS) materials and are fully biocompatible and biodegradable obviating carrier-related toxicity.

ProSilic®, our lead Bio-Courier is 100% bioabsorbable as it fully dissipates to Ortho-Silicic Acid (OSA), the bioavailable form of silicon and essential micromineral for cellular health.